Is CBD beneficial for addiction?

CBD info


The endocannabinoid system (ECS) was discovered just thirty years ago, so studies on its functioning are still in their infancy. Although it is slowly disappearing, the prohibition of the cannabis plant has seriously hampered clinical research. Cannabis is the only source of phytocannabinoids, so obtaining this study material has so far been a vetted and frustrating process.

Clinical studies on the effects of CBD are easier to carry out, since this compound can also be obtained from organic hemp. Hemp has very low THC levels, and can be grown without all the problems that surround marijuana.

The endocannabinoid system is of great interest to medical science. It has been found to be one of the major systems in maintaining homeostasis. Cannabinoid receptors are known to exist in various areas of the body. The brain, the nervous system, the immune system, and the smooth muscles of the intestine all contain CB1 or CB2 receptors.

CB1 receptors are found in the brain and nervous system in high concentrations. The endocannabinoid system has been shown to be involved in hippocampal neurogenesis and the induction of synaptic depression. CB2 receptors are found in greatest abundance in the immune system and the gut. Endocannabinoids are involved in the immune response, the stress response, appetite regulation, and thermoregulation.

There is evidence that CBD could positively affect other receptors. Serotonin and G protein receptors are also activated by CBD. They are compounds that cause a feeling of well-being. Similarly, other positive interactions are also thought to occur in areas of the body where no cannabinoid receptors are (known to be) present.


The body of research on CBD in relation to addiction is very limited. However, the positive results obtained in the first studies should prompt further research. Evidence from rodent trials indicates that the use of CBD has benefits in combating addiction to many substances.


Nicotine is a psychoactive and addictive stimulant present in tobacco. It’s even more addictive when it’s put through the industrial process by which today’s cigarettes are created. Randomized trials with human volunteers demonstrated a 40% reduction in tobacco use by subjects using a CBD inhaler. Subjects using a placebo inhaler did not reduce their cigarette consumption over the same period of time.

Enzymatic mechanisms in the brain that attenuate nicotine withdrawal symptoms are affected by ECS. Early research indicates that these mechanisms depend on CB1 receptors. CBD facilitates the production of enzymes, very promising agents for the treatment of nicotine addiction in humans.


Opioid addiction has become a huge scourge in the Western world, and has reached a critical point in many American states. Much of Europe and Australia is also facing a similar epidemic. Many people addicted to opioid pain relievers often turn to heroin and other illegal opioids to fuel their addiction.

In the complex world of life sciences, recent laboratory tests on rodents show that cannabinoids affect the way the body reacts to opioids. First, they blunt the effect of opioids on receptors in the brain.

Second, there is less inclination to relapse after the withdrawal phase. Motor function is not affected, and opioid-seeking behavior is inhibited for up to 2 weeks. The benefits of several of these tests were amplified when combined with THC.


There is very little literature on the effects of CBD on THC dependence. There is anecdotal evidence that CBD relieves feelings of anxiety caused by marijuana withdrawal. There is also evidence that CBD has beneficial effects after the withdrawal phase, and that it helps prevent relapse.

CBD-rich marijuana can modify the effects of THC. Many patients consume CBD-rich cannabis for numerous reasons. Mainly, for its therapeutic properties. In addition, CBD inhibits the “high” of THC, reducing the chances of experiencing anxiety as a side effect.


Alcohol can be very pleasant, but in the long term, it reveals itself as a toxin that negatively affects a large number of bodily functions. Alcoholic excesses and chronic alcoholism can have serious repercussions on the hippocampus and the entorhinal cortex in particular. Cognitive and behavioral problems caused by alcohol abuse may contribute to the rate of chronic relapse in alcoholics.

CBD has been shown to reduce oxidative stress and glutamate toxicity, and to act as a neuroprotectant. These neuroprotective qualities inhibit degradation of the hippocampus and entorhinal cortex during ethanol binges in rodent studies. Behavior modification is the first step in the treatment of alcoholism.

In human trials, CBD has been tested to assess its effect on alcohol toxicity. Alcohol was provided to subjects in double-blind testing. Although the feeling of “being drunk” remained the same, there was less damage to the brain.


CBD exerts its effect on various systems of the body. It affects various neural systems related to addictive disorders. It has anti-inflammatory properties and reduces oxidative stress throughout the body. So far, no negative side effects have occurred due to the administration of CBD.

Cannabidiol (and actually, cannabinoids in general) is a safe compound for humans and animals. It is extremely important for therapeutic applications. It is an easily accessible compound that affects one of the main regulating systems of the human body.

Science continues to investigate the nature of the endocannabinoid system. It seems that CBD, and the entire family of cannabinoids, are going to play a very important role in human health care in the near future.

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