There is quite a buzz around CBD. Now that cannabinoids are no longer viewed with the fear of yesteryear, science is becoming cautiously optimistic that non-psychoactive ones like CBD may have some therapeutic potential if used correctly. One area of interest is the treatment of cognitive disorders, such as Alzheimer’s and other forms of dementia. So we thought it convenient to analyze the available studies.
whatWHAT IS A COGNITIVE DISORDER?
A cognitive disorder is a disease of the brain often characterized by impairment of basic cognitive functions, such as perception, memory, language, and problem solving. The three main types of cognitive disorders are dementia, amnesia, and delusion. Other conditions such as anxiety, mood or psychosis, although they affect cognition, are not normally considered cognitive disorders
CBD AND COGNITION
Although not many studies have been carried out on the effects of CBD on amnesia and delusions, its effects on dementia, especially Alzheimer’s, are being deeply investigated. So far, the results are promising.
To explain it very simply, Alzheimer’s consists of the accumulation of plaques in neurotransmitters, preventing communication between neurons and causing their death. It is believed to be the result of oxidative stress caused by beta amyloid peptides.
This project obtained some positive results, such as that CBD provided neuroprotective and anti-apoptotic effects against amyloid beta peptides. In this experiment, cells were exposed to these peptides and cell survival was observed to be significantly decreased. Another group of cells that had received CBD before being exposed to the peptides had greater cell survival and less DNA fragmentation. Although this does not guarantee that CBD is a 100% effective treatment, it does highlight its therapeutic potential.
Obviously, this is only a research report and the studies in this matter are still recent. However, it is not the only study that has achieved positive results. For example, another project looking at the safety of medical cannabis oil found that cannabinoids appeared to be an effective treatment for both cognitive and behavioral problems associated with dementia. Other research assessed data on the effects of the endocannabinoid system on neurodegenerative modulatory mechanisms, suggesting that activation of the endocannabinoid system is the way forward for Alzheimer’s treatment. These are just some of the research projects carried out, and it is a growing trend. Scientists have set out to discover the global effects of cannabinoids on cognitive function.
Although many of these reports look at broader systems than just CBD, they show how cannabinoids can interact with the body for our benefit. Much remains to be discovered, and all clinical experiments have been done on a smaller scale, as exploration. Alzheimer’s is considered one of the leading causes of death in modern societies, and CBD may offer a solution to alleviate suffering. It is by no means a definitive answer, but it does show that more research is needed. And all of this barely takes into account how CBD’s neuroprotective characteristics could be exploited for other pathways, or how it interacts with amnesia and delirium. It’s just the tip of the iceberg!