Science is investigating cannabinoids in relation to the treatment of the symptoms and causes of diabetes. The maintenance of a balanced homeostatic system seems to be the key to the new cannabis-based treatment of this disease. There is no cure yet, but some of its symptoms can be mitigated with flowers and marijuana extracts.
Diabetes is a group of metabolic diseases caused by the body’s inability to regulate the amount of sugar, especially glucose, in the blood. Glucose levels are regulated by hormones such as insulin, which is produced in the pancreas. Diabetes can cause serious long-term complications, such as cardiovascular disease, stroke, or kidney and eye damage.
ANDTHE CANNABINOID SYSTEM IS RELATED TO BLOOD SUGAR
More and more studies are confirming the anecdotal evidence provided by people with diabetes that marijuana has beneficial effects. The anti-inflammatory properties of THC and CBD alleviate arterial inflammation, a very common symptom of diabetes, while its neuroprotective effect reduces nerve inflammation and pain. Cannabinoids also act as vasodilators, improving blood circulation and exerting an antispasmodic function on muscles and the gastrointestinal system. Restless leg syndrome caused by diabetes could also be mitigated by cannabis, making sufferers sleep better. Recent laboratory studies have shown that the endocannabinoid system could be in charge of stabilizing the blood sugar level, which is the main problem of this disease. Unfortunately, they are only laboratory research; Currently, there is no cannabis-based therapy for diabetes.
LDIABETIC MICE GET BETTER WITH MARIJUANA
Although clinical research with humans is lacking, laboratory experiments have shown a strong correlation between diabetes and cannabinoids. One of the first studies evidencing the influence of the endocannabinoid system on diabetes was published in 2006 under the title “Cannabidiol reduces the incidence of diabetes in non-obese diabetic mice”. This study indicates that CBD inhibits and delays destructive insulitis and inflammatory cytokine production, resulting in a lower incidence of diabetes.
These researchers also talk about a possible immunomodulatory mechanism that is activated by CBD. This hypothesis is confirmed by other discoveries on cannabidiol and by a study that has discovered some neuroprotective effects of CBD in an experimental model of diabetes. Other research has also found that CBD attenuates cardiac dysfunction in mice with diabetic cardiomyopathy.
A study titled “Marijuana in the Treatment of Diabetes” was published in the American Journal of Medicine in 2013. It associated current and past cannabis use with lower levels of fasting insulin, blood glucose , and insulin resistance. According to this study, cannabis users are less prone to obesity and have a lower body mass index. Cannabis smokers also had higher levels of “good” cholesterol, and a smaller waist circumference. Another important finding from this research is that marijuana users seem to have better glucose metabolism than non-users, which somewhat confirms the laboratory test results we’ve seen before.
One of the latest most important studies was carried out in 2015, when a group of scientists led by Raphael Mechoulam, known for being the discoverer of CBD, demonstrated that the anti-inflammatory properties of cannabidiol could be used to treat various diseases, including includes type 2 diabetes. And finally, **Research conducted in October 2016 showed how an experimental CBD-based treatment reduced markers of inflammation in the microcirculation of the pancreas in mice. All of these studies conclude that cannabis compounds play an important role in controlling blood sugar levels and relieving pain and other symptoms of diabetes. It is not yet known how to develop a drug from these findings.
An investigation carried out in October 2016
ARELIEF FROM THE SYMPTOMS OF DIABETES WITH CBD
Outside the lab and inside the home of diabetes sufferers, we find all kinds of anecdotal evidence showing that marijuana is effective for treating eye disease, chronic pain, sleep disorders, and other ailments associated with diabetes. The way a person with diabetes is treated also depends on whether he has other complications and his general health. Some patients supplement their therapies with cannabinoids.
Cannabis may initially whet your appetite, but in the long run it has the opposite effect and may protect against obesity. Cannabis extracts with different ratios of THC, CBD, and other cannabinoids and terpenes, or simply just CBD, are beneficial for heart and arterial health. These same cannabis or hemp extracts can be used to prepare topical creams that relieve neuropathic pain. On the other hand, a possible risk of cannabis use when suffering from diabetes is hypoglycemia, since it is feared that glucose levels will drop without the patient realizing it, until it is too late.
All types of exercise carried out on a regular basis, together with a healthy and balanced diet, reduce the risk of suffering from diabetes and serve to control the level of sugar in the blood of people with this disease. Diabetes patients should also moderate or stop their consumption of alcohol and tobacco.